If your energy, drive, focus or strength has quietly faded, low testosterone may be the cause, and it is measurable. At Longevity Marbella, testosterone replacement therapy is diagnosed with proper blood work, built around you, and monitored by a double board-certified specialist. No guesswork, no one-size-fits-all protocols.
A note on how this practice works. Hormone therapy and the modern weight loss medicines earn their results through follow-up, so here they are run as closely monitored, personal programs, never as a prescription renewed twice a year. That standard is the product, medically and in the level of service built around it, and it is deliberately for the few. If a quick prescription is all you are looking for, many clinics on the coast offer exactly that; this practice offers the alternative.
Gain muscle. Regain energy. It starts with a measurement, not a promise.
Signs you may have low testosterone
Low testosterone becomes more common with age and easily dismissed as "just getting older." If several of these feel familiar, a proper assessment with repeat morning bloodwork can give you a clear answer:
- Persistent fatigue and low energy
- Reduced libido and performance
- Low mood, irritability or lost motivation
- Brain fog and poor concentration
- Loss of muscle and strength
- Stubborn weight gain, especially around the middle
- Poor, unrefreshing sleep
Measured first. Treated second.
Done correctly, TRT is a precise medical process, and here it is built in four parts. Our approach has four parts:
- Consultation, a thorough review of your symptoms, history and goals.
- Comprehensive blood work, specialist-selected panels that confirm a diagnosis and check your wider health (not just testosterone).
- A personalized protocol, if TRT is right for you, a plan built around your results and reviewed against estradiol, hematocrit, PSA and cardiovascular markers.
- Ongoing monitoring, regular follow-up and fine-tuning to keep you safe and optimized.
The work-up, in full
The clinical name for the condition is male hypogonadism, testosterone deficiency, and the diagnosis has rules. The Endocrine Society's clinical practice guideline requires low readings to be confirmed, not assumed, and that is how it is done here:
- Two separate morning, fasting measurements. Testosterone swings with the clock and with food, so the guideline asks for confirmation, and we arrange it quickly and smoothly around your schedule.
- SHBG and calculated free testosterone when the total sits near the lower limit or a condition alters the carrier protein.
- LH and FSH, the pituitary's signal to the testes, to separate a testicular cause from a pituitary one.
- Prolactin when the pattern points to a secondary cause.
- Pituitary imaging when testosterone is severely low or other pituitary findings warrant it.
- Reversible causes hunted first: obesity, untreated sleep apnea, medications such as opioids and glucocorticoids, alcohol, iron overload, recent illness. Sometimes treating one of these is the whole treatment.
The change, in numbers. Muscle gained and fat lost, documented visit by visit. The Body Composition Assessment
Why specialist-led care matters
Your care here is directed by a doctor double board-certified in Internal Medicine and Endocrinology, deep expertise in hormones and in how the rest of your body responds to them. That means you are treated, not just monitored, and the things that matter (your heart, blood and organ markers) are watched by someone trained to read them. More on this here: GP vs endocrinologist for TRT, why who treats you matters.
The formulations, and how one is chosen
There is no single right testosterone. What exists, and what we choose between on your blood work, your SHBG, your schedule and your preference:
- Short-acting injectable esters, testosterone enanthate or cypionate, typically weekly to every two weeks. Predictable and easy to adjust; levels rise after the injection and fall toward the next one, which suits some men and bothers others.
- Long-acting injectable testosterone undecanoate, an injection roughly every ten weeks or longer once established, with the interval set by your trough level. Steady levels and few appointments; slower to correct when a dose needs changing.
- Daily transdermal gel, the steadiest physiological profile and less erythrocytosis than injections; it requires care to avoid transfer to a partner or child.
What you will not find here: implanted pellets, compounded preparations, or an aromatase inhibitor attached to every prescription by default. The guideline target is testosterone in the mid-normal range for healthy young men, reached with the formulation that fits your life, and adjusted on your own levels rather than a package.
Is testosterone therapy safe?
For men with a genuine diagnosis who are treated to normal levels and properly monitored, the evidence is reassuring. The largest trial to date found no increase in major cardiac events or prostate cancer, while recording higher rates of atrial fibrillation, kidney injury and lung clots, which is exactly why monitoring matters. Properly managed and monitored, TRT has a well-studied safety profile, but it is not exempt from possible complications, which is exactly why specialist monitoring matters. We've explained the full evidence in plain English here: Is testosterone therapy safe? What the largest study ever found. Managing those numbers, hematocrit, estradiol, blood pressure, lipids, is exactly what the double training in Internal Medicine and Endocrinology exists for, and it stands behind every prescription here.
Monitoring, in numbers
The guideline schedule, which is the schedule here: testosterone and hematocrit at 3 to 6 months after starting, at 12 months, and annually after that, with closer checks while a dose is being adjusted. Prostate risk is assessed before treatment and between 3 and 12 months after starting, where age and risk make PSA appropriate, and blood pressure and cardiovascular and metabolic markers travel alongside.
Two numbers are not negotiable. If hematocrit rises above 54 percent, therapy is stopped or reduced until it returns to a safe level and the cause is addressed. And the target is the mid-normal range, not the top of it: The target is the mid-normal range because that is where the benefit lives and the complication rate does not, with your dose set on your own levels.
Estradiol is measured when symptoms make it relevant. An elevated number on its own is not a reason for an aromatase inhibitor; the dose is corrected first.
The seven questions you should ask any TRT clinic
Independent comparisons of Marbella clinics converge on the same advice: send every clinic the same questions and compare the answers. Here are ours, in writing.
Do you require two separate morning testosterone tests before starting TRT?
Yes. The guideline standard is two fasting morning measurements on separate days, and we follow it. Arranged around your schedule, the confirmation is fast and smooth, and it is what makes the diagnosis, and everything built on it, solid.
Which baseline tests do you include, and who reviews them?
The panel described above: total testosterone twice, SHBG and calculated free testosterone where indicated, LH and FSH, prolactin when the pattern warrants it, hematocrit, PSA where age and risk make it appropriate, liver, kidney, lipid and glucose markers, and blood pressure. Every result is reviewed by the prescribing physician, me, personally.
How do you handle fertility?
It is established before any prescription is written. Testosterone suppresses sperm production, so if children are a current or future wish, the plan changes: reversible causes first, and gonadotropin-based protocols that protect fertility where treatment is needed.
What is your monitoring schedule?
It starts from the guideline schedule above: testosterone and hematocrit at 3 to 6 months, at 12 months, then annually. From there it is personalized. This is individualized medicine, and monitoring follows your case, your formulation and your response.
Which testosterone preparations do you prescribe in Spain, and why would you choose one for me?
Short-acting injectable esters, long-acting testosterone undecanoate, or daily transdermal gel, chosen on your blood work, your SHBG, your schedule and your preference, as described above. The formulation follows your case, and it can change as your needs change.
What does the first year cost, all in?
Costs are discussed transparently after your consultation, with no obligation, once it is clear what your case actually needs. Costs are discussed openly after your consultation, with no obligation, because an honest price follows the diagnosis rather than preceding it.
Under what circumstances would you defer TRT?
See the next section; it is a question every good clinic should be able to answer in writing.
When we defer
- When low testosterone is not yet confirmed. Two proper measurements make the diagnosis, whatever the symptoms.
- When a reversible cause should be treated first. Untreated sleep apnea, medication effects, iron overload, recent illness, or obesity that deserves its own plan. Sometimes that treatment is the whole answer.
- When you want children now and no fertility plan has been agreed first.
- When hematocrit is already elevated, until it is investigated and corrected.
- When there is an unresolved prostate finding or severe untreated urinary symptoms, until the urological work-up is complete.
- After a heart attack or stroke in the last six months, or with uncontrolled heart failure.
Deferred is not refused: most of these are a sequence, not a wall, and the work-up tells us which.
TRT and your fertility
Standard testosterone therapy can reduce fertility while you are on it. If you may want children, that needs to be planned for from the start, and there are protocols to help preserve fertility. Read more: How to improve male fertility.
Starting a family? Then fertility comes first, planned before anything else.
TRT is a supervised treatment: blood work is repeated through the first year and beyond, and a body composition reassessment shows muscle up and visceral fat down on paper. Blood work is repeated at regular intervals through the first year and ongoing after that, and a body composition reassessment shows whether the treatment is doing what it should: is muscle up, is visceral fat down, on paper rather than in the mirror.
Discreet, convenient, on your terms
Care that fits a demanding life: private telemedicine consultations and discreet concierge home visits across Marbella, Estepona, Puerto Banús and the Costa del Sol. English and Dutch spoken, in complete confidence.
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Frequently Asked Questions
Is TRT legal in Spain?
Yes. Testosterone replacement therapy is a legal, regulated prescription treatment in Spain when it is prescribed and monitored by a licensed doctor for a diagnosed medical need such as low testosterone (hypogonadism).
What does TRT cost at Longevity Marbella?
Cost depends on your individual protocol, which is built around your blood work and goals. We discuss everything transparently after your consultation and assessment, with no obligation.
Do you offer telemedicine and home visits?
Yes. Consultations are available by private video call, and we offer discreet concierge home visits across Marbella, Estepona, Puerto Banús and the wider Costa del Sol.
How soon will I notice results from TRT?
It varies between individuals. Many men notice improvements in energy, mood and libido within the first weeks, while changes in body composition and strength build over several months. Your response is tracked with follow-up blood work.
Is testosterone therapy safe?
For men with a confirmed diagnosis who are treated to normal levels and properly monitored, the largest trial to date found no increase in major cardiac events or prostate cancer, with monitoring still essential. Safety depends on correct diagnosis, appropriate dosing and ongoing specialist monitoring.
Who is a candidate for TRT?
Men with symptoms of low testosterone, persistent fatigue, low libido, low mood, loss of strength or focus, confirmed by blood tests. Candidacy is always determined by a doctor after assessment.
Can I just get a prescription?
Not for hormones or the modern weight loss medicines: those are run here as closely monitored, personal programs, because the follow-up is what makes them work and keeps them safe. If a quick prescription is all you need, many clinics offer exactly that; this practice offers the alternative.
Bhasin S et al. Testosterone therapy in men with hypogonadism: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2018;103(5):1715 to 1744.This page is for general information only and is not medical advice. Testosterone therapy is a prescription treatment, whether it is right for you, and how it is monitored, is always determined by a qualified doctor after individual assessment.
Considering testosterone therapy?
Speak with our specialist about properly diagnosed, monitored hormone optimization, on a private video call or a concierge home visit across the Costa del Sol.
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